The Five Best Acne Creams

In the world of beauty, faces have always been the ultimate focus. Across cultures and genders, we are always looking for ways to have the best skin. Most importantly, when acne, pimples, and zits decide to pitch camp on our faces, we do whatever it takes to find the best solution. However, everyone has different skin. Some people have aging skin, while others have allergies, and still, some just have normal skin, albeit a few zits that have popped up right before a big event. No matter what the case, we all want to feel our best, and it all starts with our face. Below is a review of the best acne creams for all types.

TreeActiv Acne Eliminating Face Cream

An All-Natural Approach to Eliminating Acne

This GMO-free, cruelty-free and vegan cream helps eliminate acne with an all-natural approach.
The Best Overall

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When it comes to fighting acne, who would have thought that all-natural was the way to go? TreeActiv did when they partnered with mother nature to give us a vegan-based acne cream that uses all-natural ingredients. Not to mention that it’s also GMO-free and cruelty-free. A big up for a healthy product that doesn’t test on animals to get you this stellar face magic. There’s a lot to love about this acne cream, not the least of which is that it draws out toxins, tightens pores, controls oil production, prevents further breakouts, and it also makes your skin creamy and smooth. I have used other all-natural products in the past, and the biggest concern was that it stripped my skin of moisture, that’s not the case with TreeActiv Acne Eliminating Face Cream. In fact, my face feels more moisturized than ever before.


  • A little goes a long way
  • Very Moisturizing 
  • All-Natural 
  • It has a gentle tingling sensation when applied to the skin.


  • It has a ginger-like odor, so if you like odorless products this might not be the one for you
  • It might not work well for very oily skin types

Terminator 10 Acne Spot Treatment

Your Acne Won't Be Back After This Termination

For tough acne that won't go away, this aggressive and fast-acting cream is just what the doctor ordered.
The Best for Cystic Acne

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If you are looking for a fast and quick fix for pimples, spots, and blemishes that have unexpectedly invaded your face, then it’s time to get the terminator! It’s aggressive and fast as it removes those unwanted new frenemies in a snap. Those blemishes will not be saying, “I’ll be back,” that’s for sure, as this product also prevents them from coming back in the future. This treatment also contains a concentrated 10 percent Benzoyl Peroxide in it, so if you have dry skin already, you will want to use a deep face moisturizer with it. It was too aggressive for my skin type, but when I used tea tree oil and several drops of jojoba oil with it, it worked wonders.


  • Fast working
  • Prevents future breakouts
  • You can use this as a spot treatment or all over your face


  • It can cause an allergic reaction for sensitive skin types
  • It can cause dryness. Make sure to moisturize with it

LilyAna Naturals Retinol Cream Moisturizer

A One-Stop-Shop to Eliminate Acne, Fine Lines & Scarring

If you are looking to fight acne while also reducing fine lines, scarring, and discoloration, then this cream will be your new best friend.
The Best for Aging Skin

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Retinol can always be a bit concerning as some treatments can dry out the skin. But there was no dryness or redness on my face after using LilyAna Naturals Retinol Cream Moisturizer because it also incorporates Vitamin E, Shea Butter, and Jojoba Oil to counterbalance any dryness that might occur. Also, I was thoroughly impressed by how it removed the dullness from my skin. This cream not only improved my acne, but it also helped repair, recover, and restore my skin’s natural radiance. It was like a one-stop-shop for the removal of fine lines, sun damage, dark spots, scars…and, most importantly, acne, of course. There are so many benefits to this face cream, especially for those of us who might have more problems than just acne.


  • Smooths fine lines and scarring
  • Gluten-Free
  • Animal Cruelty-Free


  • Retinol can cause breakouts during the first two weeks as it clears the skin

Clean & Clear Advantage Acne Spot Treatment 

You Don’t Have to Break the Bank to Have Clear Skin

If you are looking over an affordable over-the-counter product that works just as well as the more expensive brands, then this is your go-to cream.
The Best On Budget

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This is the most affordable acne product on the market with proven results. In my experience, this is the only over-the-counter product that actually works just as well as the more expensive brands. I use this product when I feel a blemish coming on and get ahead of it before it even develops. It’s super preventative and helpful to those of us who only have a few trouble areas. It’s not harsh on your skin, and you can see a visible reduction of pimples and zits within the first four hours. My biggest recommendation would be that if you have sensitive skin, only apply it once at night; otherwise, it might bother your skin.


  • Affordable 
  • Fast working


  • Fragrance can cause irritation on allergy-prone skin types

Burt’s Bees Natural Acne Solutions, Targeted Spot Treatment 

A Natural Solution For Those Oily Skin Types

This product is made for oily skin types but it still moisturizes your face and leaves it feeling silky smooth.
Best for Oily Skin Types

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This product is all-natural and gentle on your skin. It’s great for adults with occasional breakouts. This is not for an all-over acne issue, but if you just have a few spots, this is the right one for you to use. It’s lightweight and oil-free, which is excellent for people with oily skin or for those summer months when our faces don’t need a heavy cream. It doesn’t dry out your skin either. I would recommend using it at night while you sleep and using your regular moisturizer in the morning. Also, another huge plus, this product has made my skin so smooth and you can never go wrong with baby soft skin!


  • Smooth Skin
  • Gentle 
  • Oil-free


  • Does not work as fast as the other more aggressive treatments, but its more gentle on your skin

Frequently Asked Questions

When should I apply acne cream?

You should apply acne cream right after you cleanse your face. When your face is clean the cream will be able to penetrate the skin most effectively.

Can you use too much acne medicine?

A lot of people who experience drying or itching skin is because they are applying too much acne cream to their skin. If this happens, stop using so much on your skin. Always remember to read the instructions as well.

Why is moisturizer important for acne? 

Using a moisturizer every day can help your skin tolerate these medications. When your skin becomes dry, your body will produce more oil. This extra oil can block your pores leading to more breakouts. Keep your skin from becoming dry and irritated.